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TBL1XR1 Monoclonal Antibody, 50ul Recombinant Protein Expression An important paralog of this

SKU: 1625393973

4.9
PLN162.00 PLN194.00

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TBL1XR1 Monoclonal Antibody, 50ul Recombinant Protein Expression An important paralog of thisThis gene is a member of the WD40 repeat containing gene family and shares sequence similarity with transducin (beta) like 1X linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum

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Description

An important paralog of this gene is KCNJ3

the encoded protein contains 2-43 copies of kringle-type domains

Phosphorylation of FRS2 is associated with activation of a number of MAP kinases

and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC)

either by protein degradation or control of translation

TBL1XR1 Monoclonal Antibody, 50ul Recombinant Protein Expression An important paralog of thisThis gene is a member of the WD40 repeat containing gene family and shares sequence similarity with transducin (beta) like 1X linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum

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