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Enteric nervous system The ENS is an independently functioning neural system innervating the entire GI tract and containing two bundles of ganglia: one underneath the epithelial layer of the gut (submucosal plexus) and the other between the smooth muscle layers of the gut (myenteric plexus) 25

Appetite Control Research suggests that retatrutides multi-receptor activity may promote more consistent appetite regulation and metabolic balance over time